Room 401 was a television series on MTV, executive produced by Ashton Kutcher and Jason Goldberg. It was named after the room Harry Houdini died in at Detroit's Grace Hospital in 1926.

Room 401 took unaware victims into the center of mini horror movies that played out live. From the reanimation of the dead, to chain-saw mishaps, each episode contains four "scares" or pranks. The show was hosted by Jared Padalecki from the CW's Supernatural.